Scientific illustration of cerebral blood vessels and gene therapy research

Cerebral small vessel disease research and family advocacy

Building a clear path from inherited small vessel disease to targeted treatment.

CSVD Therapeutics brings families, clinicians, scientists, and therapy developers together around one urgent goal: accelerating credible treatments for genetic cerebral small vessel diseases while keeping patients at the center of the work.

The platform

A platform for CSVD families, clinicians, and scientists working toward gene-targeted therapies.

CSVD Therapeutics focuses on inherited forms of CSVD (cerebral small vessel diseases), especially COL4A1-related and NOTCH3-related disorders (CADASIL), where genetics gives us a precise starting point for therapeutic development.

Start with the leadership team, the COL4A1 and CADASIL projects, or the roadmap for research readiness.

Read more about CSVD Therapeutics
University of Sheffield Sheffield Institute for Translational Neuroscience National Institute for Health and Care Research Alzheimer's Research UK British Heart Foundation