.multicentre-hero h1 {
  font-size: 72px;
  line-height: 1.05;
}

.multicentre-lead {
  grid-template-columns: minmax(220px, 0.3fr) minmax(0, 0.7fr);
  align-items: center;
}

.multicentre-lead img {
  max-width: 340px;
  aspect-ratio: auto;
  height: auto;
}

.multicentre-lead h2 {
  font-size: 44px;
  line-height: 1.1;
}

.study-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 24px;
  align-items: start;
}

.study-card {
  min-width: 0;
  padding: 28px;
  border: 1px solid var(--line);
  background: var(--white);
}

.study-card h3 {
  margin: 12px 0 16px;
  line-height: 1.3;
}

.study-type {
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  text-transform: uppercase;
}

.study-card p {
  color: var(--muted);
}

.study-card summary {
  padding: 12px 0;
  color: var(--green);
  font-weight: 700;
  cursor: pointer;
}

.study-card details {
  border-top: 1px solid var(--line);
}

.study-card details p:first-of-type {
  margin-top: 12px;
}

.study-card a,
.research-references a {
  color: var(--teal);
  text-decoration: underline;
  text-underline-offset: 3px;
  overflow-wrap: anywhere;
}

.study-status {
  border-left: 3px solid var(--teal);
  padding-left: 12px;
  font-size: 14px;
}

.research-references {
  padding-right: clamp(20px, 7vw, 96px);
  padding-left: clamp(20px, 7vw, 96px);
  padding-bottom: 64px;
}

.research-references ol {
  max-width: 920px;
  padding-left: 24px;
}

.research-references li {
  margin-bottom: 20px;
  padding-left: 6px;
  line-height: 1.65;
}

@media (max-width: 900px) {
  .study-grid,
  .multicentre-lead {
    grid-template-columns: 1fr;
  }

  .multicentre-hero h1 {
    font-size: 46px;
  }

  .multicentre-lead h2 {
    font-size: 36px;
  }

  .multicentre-lead img {
    width: 100%;
    max-width: 320px;
    aspect-ratio: auto;
  }

  .study-card {
    padding: 22px;
  }
}