.breadcrumbs {
  margin-bottom: 24px;
  color: var(--muted);
  font-size: 13px;
  line-height: 1.5;
}

.breadcrumbs a {
  text-decoration: underline;
  text-underline-offset: 3px;
}

.disease-page .page-hero h1 {
  font-size: 64px;
  line-height: 1.05;
  overflow-wrap: break-word;
}

.disease-information h2 {
  font-size: 44px;
  line-height: 1.1;
}

.reading-references,
.publication-note {
  padding-right: clamp(20px, 7vw, 96px);
  padding-left: clamp(20px, 7vw, 96px);
}

.reading-references ol {
  max-width: 880px;
  padding-left: 24px;
}

.reading-references li {
  margin-bottom: 18px;
  line-height: 1.6;
}

.reading-references a {
  color: var(--teal);
  text-decoration: underline;
  text-underline-offset: 3px;
}

.publication-note {
  padding-top: 36px;
  padding-bottom: 48px;
  color: var(--muted);
  font-size: 14px;
}

.publication-note p {
  margin-bottom: 8px;
}

.biography-links {
  display: flex;
  flex-wrap: wrap;
  gap: 10px 18px;
  margin-top: 20px;
}

@media (max-width: 900px) {
  .disease-page .page-hero h1 {
    font-size: 40px;
  }

  .disease-information h2 {
    font-size: 34px;
  }
}